22/04/2026 - Press release
The project, led by INCLIVA, the Hospital del Mar Research Institute and the Vall d'Hebron Institute of Oncology, has developed models based on artificial intelligence and the use of liquid biopsy to molecularly characterize patients with a more aggressive phenotype. It has also been discovered that the tumor microenvironment influences resistance to chemotherapy, opening new avenues for treatments targeting both tumor cells and their surrounding environment. Among its most outstanding results, the project has enabled the development of a relapse prediction system for patients in different scenarios using artificial intelligence and deep learning, which uses models called artificial neural networks inspired by the functioning of the human brain, together with the analysis of visual images of biological tissues observed under the microscope. This helps identify high-risk patients
20/04/2026 - Events
On Wednesday, 15th April, a successful initiative to attract international postdoctoral talent to the Hospital del Mar Research Institute Barcelona (HMRIB) took place. The event, organized by Chris George and the Research Grants and Contracts Office (RGCO), was held online and saw 95 registered attendees from 61 different international institutes. The session began with a welcome address by Judit Cubedo, Managing Director of the Institute, followed by a presentation by Ismael Ávila, Head of Technology Transfer, who provided an overview of the HMRIB research environment and infrastructure. His talk highlighted the state-of-the-art facilities, the institute's translational capabilities, and the collaborative atmosphere within the PRBB research park.
Més informació "HMRIB Hosts Successful Event to Attract International Postdoctoral Talent"
20/04/2026 - General information
Initial data from this European programme, which is being carried out in Santa Coloma de Gramenet and in the Sant Martí district of Barcelona, indicate that nearly 33% of participating women have received a diagnosis of depression, compared with 20% in the case of men. The European MENTBEST project, which is being carried out in Santa Coloma de Gramenet and in the Sant Martí district of Barcelona, has now reached its halfway point after 12 months. The initial data from the study, unique in Spain and being conducted in five European countries, promoted by the European Union, show a higher prevalence of mental health problems in women.
17/04/2026 - Press release
After more than a decade of research, a new-generation CAR-T therapy developed by VHIO, in collaboration with the Hospital del Mar Research Institute, has been administered to patients for the first time in a phase 1 clinical trial. This breakthrough has been made possible thanks to continued funding from the Spanish Association Against Cancer (Asociación Española Contra el Cáncer), with the support of Ausonia, and from the Breast Cancer Research Foundation to the laboratory of Dr Joaquín Arribas at VHIO. This CAR-T combines recognition of the p95HER2 protein, which is specific to one third of HER2+ tumours, with the secretion of a bispecific antibody to activate the immune system and enhance the anti-tumour response in HER2+ solid tumours. The academic phase 1 clinical trial CATHERINE will test this therapy for the first time in patients with solid tumours overexpressing HER2 who have exhausted all therapeutic options and are candidates to receive a cell therapy. The aim is to assess safety and preliminary efficacy. The study, to be carried out at VHIO and Hospital del Mar, is funded by the Spanish Association Against Cancer, with the support of Ausonia and the Carlos III Health Institute.
14/04/2026 - Press release
At present, only around 5% of patients with colon cancer are candidates for immunotherapy. This new biomarker could make it possible to determine more accurately which individuals may receive this treatment with a likelihood of success and expand the number of patients who could benefit from it. The study, led by the Hospital del Mar Research Institute and IRB Barcelona, shows that the determination of this protein, CTHRC1, can be used to assess patient prognosis. At the same time, it opens up new avenues to approach this type of tumour. The research team has demonstrated that this biomarker can be detected using routine diagnostic tests in the clinical practice of any Pathology service.
13/04/2026 - Events
On April 14th, we will begin the third term of talks within the "Projecte Salut i Ciència", an initiative carried out in collaboration with the libraries in the reference area of Hospital del Mar. The aim is to bring science and scientific advances closer to the public through direct contact with healthcare and research professionals. The talks will be announced progressively both through the libraries and our channels: the website of the "Projecte Salut i Ciència" and social media. We look forward to seeing you!
Més informació "We are launching a new term of the "Projecte Salut i Ciència""
08/04/2026 - Press release
A new study by the Hospital del Mar Research Institute and Universitat Ramon Llull establishes for the first time a direct link between good physical fitness and a reduced risk of suffering from more than thirty diseases. The study, published in Medicine & Science in Sports & Exercise, identifies a causal relationship between a greater genetic predisposition for adequate cardiorespiratory capacity and a lower risk of developing these conditions. The results suggest that increasing aerobic activity may provide protection against various cardiovascular, inflammatory, and other diseases.
Més informació "Being physically fit helps prevent diseases"
24/03/2026 - Events
Hospital del Mar Research Institute is organising four visits to discover two of the projects funded by La Marató. Have you signed up yet? Hospital del Mar Research Institute is once again taking part in the initiative "Visita la recerca de La Marató", promoted by the Fundació La Marató de TV3, opening its doors and bringing biomedical research closer to the public in order to show the impact of the projects funded thanks to solidarity. In this edition, the institute is organising four guided visits between May and June, two in the morning and two in the afternoon. The aim is to present two projects funded through the 2021 Mental Health La Marató and the 2022 Cardiovascular Health La Marató, focused on two major health challenges: suicide prevention and stroke.
Més informació "Come and learn firsthand about the research promoted by La Marató."
Agustín Conesa Celdran, Sara Mederos and Sílvia Susín Calle have been selected in the 2025 edition of these grants. The award ceremony took place on March 17 at the CosmoCaixa Science Museum. The "la Caixa" Foundation has awarded one hundred new doctoral and postdoctoral fellowships to outstanding researchers who will carry out their projects at research centres in Spain and Portugal, three of them to researchers at Hospital del Mar Research Institute. These are Agustín Conesa Celdran and Sílvia Susín Calle, who received the INPhINIT doctoral fellowship, and Sara Mederos, who received the Junior Leader postdoctoral fellowship. The aim of these grants is to retain and attract talent in order to promote excellence in research in these countries.
10/03/2026 - Press release
The absence of a protein, the kinase IKKα, enables tumor cells to cluster and survive during dissemination. The findings, published in Nature Communications, open the door to new prognostic markers and potential therapeutic strategies. Targeting tumor cell adhesion impairs their ability to migrate and form metastases. The study was conducted using a preclinical mouse model
Més informació "Researchers identify a key mechanism that promotes colorectal cancer metastasis"
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