06/03/2024 - Press release
Between 1990 and 2019, the incidence of myocardial infarction in the Girona area decreased by 1% in women and 4% in men each year in the population aged 35 to 74 years, while, in the last 10 years, its lethality, the number of people who die 28 days after the onset of symptoms, has remained stagnant at around 15%. Data from almost five million hospital admissions and more than 70,000 death certificates have been analyzed as part of the REGICOR study, Registre Gironí del COR. These data suggest that primary prevention and rapidity of care have contributed to reducing the incidence of infarction and sudden death, increasing the chances of survival among patients arriving at the hospital.
Més informació "Decline in the mortality rate of people who suffer myocardial infarction stalls"
21/02/2024 - Press release
This is an international collaborative work coordinated by the Hospital del Mar Research Institut and the Hospital Clínic-IDIBAPS, published in the Journal of Neurology. This new tool may make it possible to adapt the monitoring and treatment of patients to their future evolution, opting for the most effective, but with more possible side effects in those with worse prognosis. The exact factors behind the progression of disability in multiple sclerosis, a disease with great heterogeneity, are unknown, which is why it is so important to have tools of this type.
15/02/2024 - Press release
A study by Hospital del Mar and Hospital General de Catalunya shows that this new type of device is three times more effective than previous models in completely closing the aneurysm. Moreover, in a safe way. It is published in the Journal of Neurointerventional Surgery. The new generation of stents for the treatment of cerebral aneurysms is more effective and safer, according to a study by Hospital del Mar and Hospital General de Catalunya that has just been published in the Journal of Neurointerventional Surgery. In fact, they are three times more effective, with practically no complications.
Més informació "Efficacy of the new generation of stents to treat cerebral aneurysm validated"
09/02/2024 - Press release
An international study has used a computational biology tool that, by analysing a multitude of biological data from multiple sclerosis patients ranging from genetic information to the whole organism, reveals the relationship between elements of different biological scales and improves our knowledge and the diagnosis of the disease. International research led by the Department of Medicine and Life Sciences (MELIS) at Pompeu Fabra University, in collaboration with Hospital del Mar, Hospital Clínic, Charité - Medical University of Berlin, and the universities of Oslo and Genoa, has developed a computational biology tool, based on multi-level network analysis, to achieve an integrated vision of multiple sclerosis. This tool could be used to study other complex diseases such as types of dementia.
30/01/2024 - Press release
This is revealed by the largest observational study in this field carried out to date in the world. It is published in the journal Nutrients. The work is based on data from the UK Biobank database and has made it possible to analyze information from more than 260,000 people. Its conclusions may allow a more detailed definition of future studies on omega-3 supplementation for the prevention of dementia. The potential benefits of these fatty acids are maximal in men over 60 and in dementias other than Alzheimer's disease.
10/01/2024 - Press release
Functional alterations in the brains of individuals with this condition coincide with the distribution of these neurons in the same brain. These neurons are responsible for filtering external information reaching the brain. Their functioning is altered in individuals with schizophrenia, which explains the majority of their symptoms. This discovery is the first time that this alteration can be identified as a possible origin of schizophrenic symptoms, and it opens the door to seeking new targeted treatments with fewer patient side effects.
28/12/2023 - Press release
An observational study conducted by researchers from Pompeu Fabra University and Hospital del Mar determines that the intradermal administration of the JYNNEOS vaccine against smallpox induces an efficient immune response that should protect people living with HIV from contracting the monkeypox virus.
Researchers from the Hospital del Mar Research Institute have published a new article in Microbiology Spectrum proposing a novel approach to treating pneumonia caused by antibiotic-resistant Pseudomonas aeruginosa bacteria. The study suggests that increasing the dose of the antibiotic colistin may not only be ineffective, but could also increase patient mortality. For this reason, the researchers advocate for using nebulized administration of the treatment instead of intravenous administration. This approach achieves higher concentrations in the lungs, where the infection is located, without causing toxic colistin concentrations in the blood. The World Health Organization considers antibiotic resistance among the top 10 global public health threats.
A study involving the Hospital del Mar Research Institute, the Vall d'Hebron Institut d'Oncologia, IDIBELL, and the Institut Català d'Oncologia suggests that combining chemotherapy with drugs that can inhibit two cell signaling pathways involved in tumor progression may aid in treatment. The research has analyzed the interaction of the protein IKKα with these pathways, known for their ability to promote the proliferation of tumor cells. This combination has the advantage of reducing treatment toxicity. The study opens the door to new approaches for tumors with the presence of this protein. It is published in the EMBO Journal.
Més informació "A possible new combination of treatments to combat cancer"
05/10/2023 - Press release
A study led by researchers at the Hospital del Mar Research Institute identifies that the deterioration of the blood-brain barrier, which regulates exchanges between the blood and the brain, can be used to identify which of these patients will have a more rapid progression. In the patients analysed, the risk of accelerated disease progression increases by 8% for every 10% increase in the level of albumin in cerebrospinal fluid and blood (a biomarker of damage to the blood-brain barrier). The results indicate that restoring the blood-brain barrier's ability to protect the brain could help slow the worsening of patients. This marker will allow a more accurate assessment of the prognosis of patients with cognitive impairment caused by Alzheimer's and other dementias. The work is published in the journal Alzheimer's&Dementia.
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