05/02/2026 - Press release
A recent study from the Hospital del Mar Research Institute shows that cannabis use is associated with increased brain inflammation, which may affect the therapeutic effectiveness of antipsychotic treatments. The study analysed brain MRI scans from nearly 100 individuals-patients with first-episode psychosis and healthy volunteers-using a novel technique that measures extracellular free water. This is the first study to apply this method to examine the effects of cannabis use in psychosis. The findings are published in Molecular Psychiatry and reinforce recommendations against cannabis use in people with psychotic disorders.
Més informació "Cannabis use may influence treatment mechanisms in first-episode psychosis"
05/02/2026 - Press release
Infections caused by Enterobacterales, Pseudomonas aeruginosa and Acinetobacter baumannii are identified as priorities for clinical research. The study, published in the Journal of Infection and Public Health, involved 60 experts who reached consensus on the main priorities for the development of new clinical trials. The work carried out within the MePRAM project of CIBER has resulted in several priority lists-microorganisms, clinical syndromes, patient populations and anti-infective treatments-aimed at guiding future research from a personalised medicine approach.
Més informació "The roadmap for clinical research against antibiotic resistance established"
03/02/2026 - Press release
A research team from the Parc Taulí Research and Innovation Institute (I3PT), in collaboration with the Pere Virgili Health Research Institute (IISPV) and the Hospital del Mar Research Institute (HMRIB), has identified a clear association between the accumulation of abdominal fat and premature vascular aging in people with type 1 diabetes who have no previous history of cardiovascular disease. The research was based on a cohort of 179 individuals with this condition, all of whom were assessed at Parc Taulí University Hospital. Despite having good control of blood glucose levels, blood pressure, and lipid profile, approximately 10% of the individuals studied showed signs of premature vascular aging-a key factor in the development of cardiovascular and microvascular complications that directly affect quality of life and life expectancy.
Més informació "Abdominal fat is associated with premature vascular aging in type 1 diabetes"
26/01/2026 - Press release
Deaths among patients with acute myocardial infarction before reaching hospital were reduced, during the response by the Medical Emergency System of Catalonia (SEM), by 20% during this period, compared with what would have been expected in the period prior to the implementation of this initiative. Overall, 28-day mortality after suffering a heart attack decreased significantly, falling from 27% of cases to 19%. These findings are highlighted in a study by researchers from the Hospital del Mar Research Institute, in collaboration with Hospital de Sant Pau and Hospital Clínic de Barcelona, which analysed data from 100,000 people who suffered a heart attack in Catalonia between 2008 and 2019.
16/01/2026 - Press release
Researchers from the Hospital del Mar Research Institute and the Vall d'Hebron Institute of Oncology have demonstrated, in animal models, the role played by these cells in the development of cancer cells. The study, published in Science Advances, shows that eliminating these cells at an early stage of tumor growth promotes tumor proliferation and the formation of metastases. By contrast, combining their elimination with an inhibitor of the CCL2 molecule reduces tumor size and eliminates metastases.
16/12/2025 - Press release
It aims to develop the first treatment based on mRNA therapy to boost the efficacy of immunotherapy for this type of tumour. The new company, a spin-off of the Hospital del Mar Research Institute Barcelona, plans to launch its first human clinical trial in 2028 to validate the safety of this approach. The project is led by Drs. Toni Celià-Terrassa and Joan Albanell, pioneers in the development of nanotherapies designed to transform tumours that are resistant to immunotherapy into tumours that are vulnerable to treatment.
16/12/2025 - Press release
These are some of the conclusions of the report "Working on digital platforms: What do we know about health and safety?", a joint study by UPF and the Hospital del Mar Research Institute Barcelona, within the framework of the international project GIG-OSH, which has collected data from seven European countries.
12/12/2025 - Press release
Having a higher proportion of fatty acids in the blood from a healthy diet reduces the risk of suffering from this type of stroke by 14%. The researchers have established an index that measures more reliably than other systems used the quality of fats in the diet of the studied individuals. The work is published in the European Stroke Journal. Blood fat levels can be calculated from a simple blood test. This opens the door to its application in clinical practice.
Més informació "They design a tool to predict the risk of ischemic stroke from blood fats"
11/12/2025 - Press release
The research team led by the Institut de Recerca Joan de Déu (IRSJD) and the Hospital del Mar Research Institute has, for the first time, demonstrated the efficacy of a drug in animal models developed from samples of patients from the Sant Joan de Déu Hospital. The study identifies the PRKG1 gene as a key element in the biology of rhabdomyosarcoma and as a potential biomarker to predict treatment response. The determination of Cristina's parents-a girl who passed away from rhabdomyosarcoma in 2015-has been crucial in making this study possible. Their commitment enabled the raising of more than €600,000 to promote research into new treatments for this type of pediatric tumor.
04/12/2025 - Press release
A study from the Hospital del Mar Research Institute, published in The Journal of Clinical Investigation, indicates that the high expression of the estrogen receptor is the main factor preventing the most common type of breast cancer, luminal breast cancer, from responding to immunotherapy. The high presence of the estrogen receptor sequesters the LCOR molecule, whose action on tumor cells is necessary to make tumors visible to the immune system. In experimental models, the researchers found that combining immunotherapy with endocrine therapy allows LCOR to function and the immune system to attack the tumor. At the same time, they have generated a modified version of the LCOR molecule that sensitizes tumors to immunotherapy, including those with hormone receptors. The next goal is to study this molecule combined with immunotherapy in clinical trials.
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